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Beta-Blockers & Kidney Disease

Kidney disease is one of the major risk factors for high blood pressure (hypertension). If hypertension develops, it may be necessary to use beta-blockers to reduce blood pressure levels and prevent additional kidney damage.

  1. Types

    • Several beta-blockers are used to treat high blood pressure associated with kidney disease. These drugs include: metoprolol, atenolol, labetalol, sotalol, pindolol, acebutolol, timolol and carvedilol.

    Function

    • Beta-blockers reduce blood pressure by blocking the effects of epinephrine on the heart. These drugs also cause the blood vessels to dilate, which improves circulation. Increased blood flow to the kidneys slows the progression of kidney disease and may prevent chronic renal failure or death.

    Side Effects

    • The American Heart Association reports that beta-blockers can cause cold hands, fatigue, weakness and dizziness. These drugs may also cause insomnia, shortness of breath, depression and reduced libido.

    Risks

    • The Mayo Clinic indicates that beta-blockers may increase triglyceride levels and decrease levels of high-density lipoprotein (LDL), the good cholesterol in the blood. These changes are usually mild and temporary. Blood pressure may drop too low while taking a beta-blocker. Report weakness, fatigue, lightheadedness, dizziness and other symptoms of low blood pressure (hypotension) to your doctor.

    Considerations

    • You may not be able to take a beta-blocker if you have an abnormal heart rhythm or partial block of the AV node, according to Dr. Richard Klabunde, a professor at Ohio University College of Osteopathic Medicine. Discuss other treatment options with your health-care provider.

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