What causes hives to flare up with lupus?
Several factors can trigger hives (urticaria) in individuals with lupus:
1. Autoimmune Response: In lupus, the immune system malfunctions and mistakenly attacks the body's own tissues. This autoimmune reaction can cause the release of histamine and other inflammatory mediators, leading to the development of hives.
2. Medications: Some medications commonly used to treat lupus, such as non-steroidal anti-inflammatory drugs (NSAIDs), antibiotics, and certain chemotherapy drugs, can trigger hives as a side effect.
3. Stress: Emotional stress can exacerbate lupus symptoms, including hives. When a person with lupus experiences stress, their immune system can become overactive, leading to the release of inflammatory chemicals and the development of hives.
4. Infections: Infections, such as viral or bacterial illnesses, can trigger hives in individuals with lupus. The inflammatory response associated with infections can worsen lupus symptoms, including the appearance of hives.
5. Allergies: People with lupus may be more prone to developing allergies, which can also cause hives. Allergies to foods, pollen, dust, or other allergens can trigger the release of histamine and lead to the formation of hives.
6. Sunlight Exposure: Some individuals with lupus experience photosensitivity, which means that their skin becomes more sensitive to sunlight. Exposure to ultraviolet (UV) rays from the sun can worsen lupus symptoms and trigger hives.
7. Hormonal Changes: Fluctuations in hormone levels, particularly during menstruation or pregnancy, can contribute to lupus flares and the development of hives.
8. Certain Foods: Specific foods, such as nuts, shellfish, eggs, and dairy products, can trigger hives in some individuals with lupus. This reaction is often associated with an underlying food allergy or intolerance.
It is important for individuals with lupus to work closely with their healthcare provider to identify and manage triggers that may cause their hives to flare up. Proper medical care, medication management, and lifestyle modifications can help reduce the occurrence of hives and improve overall well-being in people with lupus.