Cushing's Disease Symptoms in People

Cushing's disease is a hormonal disorder that develops in people who have had prolonged exposure to high levels of the hormone cortisol. In some cases, the body produces too much cortisol. Cushing's disease can also occur in people who take medications classified as corticosteroids for long periods. The condition, which is also called Cushing's syndrome, is most common in people between the ages of 20 and 50. Obesity and Type 2 diabetes are risk factors for developing Cushing's disease.

Obesity

• People who have Cushing's disease tend to be overweight or experience a sudden weight gain. The extra weight is usually carried in the upper body or around the abdomen. People with Cushing's also develop a round face and may get a fatty hump or bump between their shoulders. Despite the extra weight, people with Cushing's often have thin arms and legs. In children with the condition, growth rates are slower than normal.

Skin Problems

• Cushing's disease can cause many changes to the skin. It tends to become thin and will bruise easily. Cuts, scrapes and other skin lesions heal slowly, and pink or purple stretch marks may develop on the legs, back, abdomen, breasts and buttocks.

Female Symptoms

• Women with Cushing's disease often experience symptoms unique to females. Many women will grow excess hair on their face, neck, thighs, abdomen and chest. In addition, menstrual periods may become irregular or stop occurring.

Male Symptoms

• In men with Cushing's disease, erectile dysfunction may become a problem. Fertility can be affected as well, and some men with the condition may have a decreased desire for sex.

Other Symptoms

• Among the other common symptoms of Cushing's disease are bone fractures, headaches, high blood pressure, acne, muscle weakness, fatigue, high blood glucose, depression and increased thirst and urination.