What results of esophageal function tests indicate a normal condition?

The following results of esophageal function testing are indicative of a normal condition:

Esophageal Manometry:

- Normal resting pressure of the lower esophageal sphincter (LES): 10-20 mmHg.

- Normal peristaltic waves with an amplitude greater than 30 mmHg and a duration of 2-8 seconds.

- Absence of premature contractions or ineffective esophageal contractions.

- Normal relaxation of the LES during swallowing.

24-Hour Esophageal pH Monitoring:

- Acid exposure time (AET) less than 4.0% of the total monitoring time.

- Number of reflux episodes less than 50.

- Absence of prolonged acid reflux episodes (lasting longer than 5 minutes).

Esophageal Impedance-pH Monitoring:

- Normal baseline impedance patterns with a stepwise decrease during swallowing.

- Absence of excessive non-acid reflux episodes (supragastric belching, gas reflux).

Esophagogastroduodenoscopy (EGD):

- Normal appearance of the esophageal mucosa without any signs of inflammation, erosion, or ulcers.

- Absence of hiatal hernia or other structural abnormalities.

It's important to note that the interpretation of esophageal function test results should always be done in the context of the patient's symptoms and overall clinical presentation.