What neurotransmitter creates migraines?

The precise mechanisms underlying migraine headaches are complex and involve various factors. While serotonin is often associated with migraines, it is not accurate to state that a specific neurotransmitter solely causes migraines. Rather, an imbalance or dysregulation of several neurotransmitters and brain chemicals, including serotonin, play a role.

Serotonin is a neurotransmitter involved in transmitting signals between nerve cells and regulating various bodily functions, including mood, appetite, and sleep. During migraine episodes, serotonin levels in the brain may fluctuate, contributing to the symptoms experienced.

However, it is essential to understand that migraines involve a combination of genetic, environmental, and physiological factors. Alterations in other neurotransmitters, such as dopamine, glutamate, and calcitonin gene-related peptide (CGRP), along with changes in blood flow, inflammation, and brain activity, also play significant roles in the development of migraines.

Therefore, it is not accurate to attribute migraines solely to one specific neurotransmitter. Instead, migraines result from a complex interplay of various neurotransmitters, brain chemicals, and physiological mechanisms.