Leg Weakness in MS

Multiple sclerosis, or MS, is a chronic inflammatory disease affecting the central nervous system, according to Baylor University Medical Center. MS is seen in approximately 6 people in every 10,000, and is more common in cooler climates.

Paresis

• Weakness in the leg muscles of MS patients is also known as paresis, which is the medical term for partial or mild paralysis, according to the group All About Multiple Sclerosis. It is a common symptom of MS.

Atrophy

• As messages to the legs are blocked during MS, the muscles are used less, resulting in atrophy.

Cause

• Leg weakness in MS is caused by blocked or poorly transmitted messages from the brain and spinal cord. Lesions on the spinal cord and brain block the transmission of messages to muscles in the legs, leading to wasting of the muscles, according to the British charity Multiple Sclerosis Trust.

Areas

• Lesions affect common nerve pathways of the cerebella, the brainstem and the spinal cord, according to All About Multiple Sclerosis.

Problems

• Leg weakness and reduced muscle mass in the legs can result in other problems, which the Multiple Sclerosis Trust lists as difficulties balancing and walking. An increase in existing bowel problems also can result. Leg weakness can worsen fatigue problems.