Risks of Copaxone

Copaxone is an injectable form of glatiramer acetate that is prescribed to treat relapsing-remitting multiple sclerosis. According to the manufacturer, Teva Pharmaceutical Industries, Copaxone “is usually well-tolerated, has a lower incidence of side effects than other medications, and …is thought to work both outside and inside the central nervous system (CNS) to fight damage to the nervous system.” However, as with any medication, Copaxone does carry some risks and side effects.

Injection Reactions

• The most common side effect of Copaxone involves a short-term reaction that appears soon after injection. This reaction usually causes flushing, skin rash or swelling at the injection site that diminish in about 15 to 20 minutes after dosing. Some patients have reported heart palpitations, chest tightness or trouble breathing as part of these initial reactions; however, you should contact your doctor immediately if these symptoms do not disappear after a few minutes or if you suddenly get these types of symptoms. Irregular heart rhythms, trouble breathing or severe pain can indicate a serious reaction that can put your health at risk.

Skin Indentations

• A small, permanent indentation or dimple in the skin around a commonly used injection site has also been reported by patients on Copaxone. Injection of Copaxone can destroy underlying, protective body fat tissue. Contact your health care provider if you notice any skin changes while taking Copaxone.

Pregnancy and Breast Feeding

• Most of the data regarding Copaxone and pregnancy or during breast feeding has been anecdotal. According to the manufacturer, use has not been studied in pregnant women, and there is not sufficient data to determine if the drug is passed into breast milk. If you are taking Copaxone and become pregnant or are planning to breastfeed, you should speak with your health care provider regarding the risks to both you and your unborn child of continuing therapy.