Permanent Reflex Damage Due to Chemo

Reflex damage is a symptom of a wider nerve damage condition known as chemotherapy-induced peripheral neuropathy, or CIPN. This condition occurs when drugs administered during treatment accidentally damage healthy cells such as nerve cells.

How Does Chemotherapy Affect the Body?

• Chemotherapy involves the administration of drugs that kill fast-growing or rapidly dividing cells. Cancerous cells are one type that are fast-growing, but other types of healthy cells, such as those in bone marrow and hair follicles, can also be damaged.

Nerve Damage

• Nerve cells are not classified as fast-growing cells---they are simply more delicate than other types of cells. They can become damaged during the administration of chemotherapy, resulting in chemotherapy-induced neuropathy.

Symptoms

• Delayed or weak reflex response is a symptom of chemotherapy-induced nerve damage. Complementary symptoms include phantom sensations of pain, burning or pins and needles, muscle weakness and general numbness.

Prevention

• There is no easy way to prevent this type of nerve damage. Some evidence suggests administration of a drug called amifostine before chemotherapy can protect nerves and tissues from damage. In addition, calcium and magnesium can help prevent nerve damage when administered intravenously.

Treatment

• Existing nerve damage is often permanent but can be reduced with a combination of medications and supplements. Physical therapy may help muscles regain strength and train nerves to respond properly to stimuli.