What causes parkinsons?

Parkinson's disease is caused by a loss of nerve cells (neurons) in the part of the brain called the substantia nigra. These neurons produce a chemical messenger in your brain called dopamine. When the body doesn't produce enough dopamine, it causes abnormal brain activity, leading to tremors, stiffness, and difficulty with balance and coordination.

The exact cause of this neuron loss is unknown, but several factors are believed to play a role, including:

1. Genetics: Some people are more likely to develop Parkinson's disease because of their genes. However, most cases of Parkinson's are not directly inherited.

2. Environmental factors: Exposure to certain toxins and chemicals, such as pesticides, herbicides, and certain metals, has been linked to an increased risk of Parkinson's disease.

3. Age: The risk of Parkinson's disease increases with age. Most people with Parkinson's are diagnosed after age 60.

4. Other factors: Head injuries, inflammation, and oxidative stress (an imbalance between the production of free radicals and the body's ability to counteract them) have also been suggested as possible contributing factors.

It's important to note that Parkinson's disease is a complex disorder, and the exact cause is not yet fully understood. Ongoing research is working to uncover the precise mechanisms behind the development of Parkinson's disease to find better treatments and prevention strategies.