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PSP & Parkinson's

Progressive supranuclear palsy (PSP) and Parkinson's disease are brain disorders that share many common symptoms, according to the National Institute of Neurological Disorders and Stroke (NINDS). Although the two disorders share some common symptoms, they are each distinct neurological conditions with different prognoses and treatment options.

  1. Identification

    • The diagnosis of PSP and Parkinson's disease is one area where the two brain disorders differ greatly. Identifying Parkinson's involves a series of neurological tests which test reflexes, movements and reactions, according to the Worldwide Education and Awareness for Movement Disorders. In contrast, states the Mayo Clinic, PSP cannot be diagnosed directly, only by ruling out other medical conditions.

    Effects

    • PSP affects the region of the brain known as the brain stem, and causes deterioration of the cells in that area. While Parkinson's disease also affects the brain stem, it is also responsible for reduced production of dopamine by destroying neurons in the brain which produce this neurotransmitter.

    Features

    • Clumsiness, stiffness, and difficulty moving are symptoms characteristic of both PSP and Parkinson's Disease, states the NINDS. Those suffering from PSP, however, tend to tilt and fall over backward while people with Parkinson's commonly bend forward. Swallowing, speech, and especially eye movement are affected more severely with PSP than with Parkinson's, although both disorders cause difficulties with these.

    Time Frame

    • Both PSP and Parkinson's disease typically show up in people over 60 years of age. The two brain disorders are progressive, with symptoms becoming more severe over time. According to the NINDS, there is no cure for either disease, although Parkinson's symptoms can be managed with treatment.

    Potential

    • Although medications are a valuable treatment for Parkinson's, there is no effective treatment for PSP, states the NINDS. However, the NINDS is currently conducting experimental research to find the cause of PSP, which may yield effective treatment options.

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