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Genetic Causation Involved in Parkinson's Disease

Parkinson's disease is considered to be idiopathic, meaning that its overall cause is unknown. In some cases, however, there does appear to be a genetic (inherited) component in the development of the disease.

  1. Impact

    • Between 15 and 20 percent of people who develop Parkinson's disease also have a family history of the condition, according to Merck Manuals.

    Features

    • Merck Manuals reports that autosomal (non-sex chromosomal) dominant and recessive genes have been identified to the development of Parkinson's disease.

    Significance

    • Rather than causing Parkinson's disease, some inherited characteristics may make people more susceptible to developing the condition, according to the Cleveland Clinic.

    Age

    • It appears that the form of Parkinson's disease that runs in families affects younger people (Parkinson's mostly affects people over the age of 50), according to Medline Plus.

    Risk Factors

    • Other risk factors for Parkinson's disease include sex, as men are at a somewhat increased risk, and exposure over time to herbicides and pesticides, according to the Mayo Clinic.

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