Genetic Causation Involved in Parkinson's Disease

Parkinson's disease is considered to be idiopathic, meaning that its overall cause is unknown. In some cases, however, there does appear to be a genetic (inherited) component in the development of the disease.

Impact

• Between 15 and 20 percent of people who develop Parkinson's disease also have a family history of the condition, according to Merck Manuals.

Features

• Merck Manuals reports that autosomal (non-sex chromosomal) dominant and recessive genes have been identified to the development of Parkinson's disease.

Significance

• Rather than causing Parkinson's disease, some inherited characteristics may make people more susceptible to developing the condition, according to the Cleveland Clinic.

Age

• It appears that the form of Parkinson's disease that runs in families affects younger people (Parkinson's mostly affects people over the age of 50), according to Medline Plus.

Risk Factors

• Other risk factors for Parkinson's disease include sex, as men are at a somewhat increased risk, and exposure over time to herbicides and pesticides, according to the Mayo Clinic.