Topical Pain Relief for Neuropathy

Neuropathy is a term used to describe damage to the central nervous system or to the related peripheral nervous system. Pain is a frequent symptom of neuropathic damage. Unlike pain that results from direct stimulation of the pain receptors, neuropathic pain is a result of problems in the nerves themselves. In some cases this pain may be at least partially controlled through use of topical medications.
  1. Causes of Neuropathy

    • Your neuropathy symptoms may result from a number of causes. According to the Merck Manuals Online Medical Library, potential causes include post-surgical complications, central nervous pain syndromes and an ailment called complex regional pain syndrome. The National Institute of Neurological Disorders and Stroke lists additional causes, including systemic diseases such as diabetes and various metabolic disorders, infection, autoimmune disorders, inherited neuropathy and direct physical injury.

    Capsaicin Treatments

    • In some circumstances, your doctor may choose to control your pain with topical medications. If your neuropathy pain is relatively minor, your treatment may begin with an over-the-counter pain reliever (analgesic) called capsaicin, which is derived from the seeds of hot chili peppers. It is believed that capsaicin achieves its effects by reducing your nerve cells' ability to send pain messages to your brain. Common capsaicin-based products include Capsazin, Zostrix and Capsin. Typically, these medications are most effective when your pain is located close to the surface of your skin. Relief from capsaicin is temporary, and you may need to reapply cream, lotion or gel several times throughout the day.

    Lidocaine Treatments

    • If your pain is worse, or otherwise difficult to treat, your doctor may choose to treat you with the prescription local anesthetic lidocaine, which in its topical form is also known as Lidoderm. This medication is typically applied directly to the site of your pain in the form of a patch. While Lidoderm is often effective, it may also cause serious side effects, including confusion, drowsiness, irregular heartbeat, seizures, tremors or blurred vision. If you are allergic to lidocaine, Lidoderm use may also trigger symptoms, including swelling of your tongue, throat, lips or face; hives and breathing difficulties. If you experience any of these signs, seek medical attention immediately.

      It is also possible to overdose on Lidoderm. For this reason, it is vital that you follow both your doctor's guidelines and the instructions that come with your medication. Do not place bandages, heating pads or other coverings over your Lidoderm patch unless your doctor specifically instructs you to do so. Additionally, do not use Lidoderm on large areas of skin, or on skin that is swollen or seriously punctured. Consult your doctor for additional treatment guidelines.

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