Does lipedema which is also known as painful fat syndrome mostly affect women?

Yes, lipedema, also known as painful fat syndrome, primarily affects women. It is a chronic condition characterized by the abnormal accumulation of fat deposits, usually in the legs and buttocks, sometimes extending to the arms. While it can occur in men, lipedema predominantly affects women, often beginning during puberty, pregnancy, or menopause. The exact cause of lipedema is not fully understood, but hormonal factors, genetics, and other underlying medical conditions are believed to play a role.