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Side Effects of Meridia

Meridia (sibutramine hydrochloride monohydrate) is prescribed to achieve and maintain weight loss in obese patients. It is intended and recommended for patients with a body mass index (BMI) greater than 30, or 27 if other health risks are present. Like most medications, some side effects are possible if you take Meridia.

  1. Function

    • Meridia works by inhibiting the reuptake of the neurotransmitters serotonin, dopamine and norepinephrine, which are chemicals of the brain that affect hunger.

    Common Side Effects

    • Common side effects include sleep disruption, dry mouth, headache, loss of appetite and constipation.

    Serious Side Effects

    • Serious side effects that have been reported include seizures, bleeding, an increase in blood pressure or heart rate, and a rare condition called "serotonin syndrome," which can be life threatening. According to the Food and Drug Administration, reported allergic reactions include hives, angioedema and anaphylaxis.

    Warning

    • According to the FDA, blood pressure and/or pulse rate can significantly increase in some patients. Blood pressure and pulse rate should be monitored while taking Meridia.

    Consideration

    • Meridia is classified and controlled as a Schedule IV drug under the Controlled Substances Act. Abuse may lead to limited physical or psychological dependence.

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