Can taking fosamax while receiving a local with epinepherine cause osteonecrosis of the jaw?

Osteonecrosis of the jaw (ONJ) is a rare but serious condition that can occur in people who are taking certain medications, including bisphosphonates (such as Fosamax) and corticosteroids. ONJ is a condition in which the jawbone becomes exposed and dies. It can cause pain, swelling, and infection.

In most cases, ONJ occurs in people who have been taking bisphosphonates for a long time (more than 3 years) and who have also received radiation therapy to the head and neck area. However, ONJ has also been reported in people who have only taken bisphosphonates for a short time and in people who have not received radiation therapy.

The exact cause of ONJ is not fully understood, but it is thought that bisphosphonates may interfere with the normal blood supply to the jawbone. This can lead to the death of bone tissue and the development of ONJ.

The risk of ONJ is increased in people who have certain other conditions, such as diabetes, gum disease, and osteoporosis. People who smoke or drink alcohol are also at increased risk of ONJ.

If you are taking a bisphosphonate and you experience any of the following symptoms, you should contact your doctor immediately:

* Pain in the jaw

* Swelling in the jaw

* Bleeding from the gums

* Loose teeth

* Exposed bone in the jaw

Your doctor will evaluate your symptoms and determine if you have ONJ. If you do have ONJ, your doctor will recommend treatment options. Treatment options may include:

* Stopping the bisphosphonate

* Antibiotics to treat infection

* Surgery to remove dead bone tissue

* Hyperbaric oxygen therapy

ONJ is a serious condition, but it can be treated successfully if it is caught early. If you are taking a bisphosphonate, be sure to talk to your doctor about the risks of ONJ and how to prevent it.