Focal Chronic & Acute Inflammation

Inflammation is the body’s response to tissue damage. Closely linked with the repair process, inflammation occurs in an attempt to stop the cause of the tissue damage and mitigate its effects. It can be acute or chronic, and can occur over a widespread area or locally. Locally occurring inflammation is referred to as “focal”.

Acute vs. Chronic

• Acute inflammation comes on suddenly and lasts a short period of time, while chronic inflammation builds gradually and becomes a long-term problem.

Acute Inflammation

• Acute inflammation is characterized by increased blood flow to the injured area, along with the accumulation of white blood cells. The injury may heal, form an abscess or progress and become chronic.

Chronic Inflammation

• Chronic inflammation is the result of simultaneous tissue destruction and repair, as in the case of arthritis. It can be the result of infection, exposure to toxins or an autoimmune response.

Vasodilation

• The brief constriction then dilation of the blood vessels surrounding the focal injury lead to increased localized blood flow. This is why inflamed areas become red and warm.

Inflammation Mediators

• Histamine and serotonin are two chemicals produced by the body that help regulate the inflammation process.