What is codeine contin. I take 200mg twice a day for more than 4yrs should be worried?

Codeine Contin (codeine sulfate extended-release tablets) is used to relieve moderate to severe pain and may also be used as a component of cough medicines. However, taking high doses of codeine, including 200mg twice a day for more than 4 years, may raise concerns about potential complications.

1. Risk of Addiction:

Frequent and high-dose use of codeine can lead to physical and psychological dependence. Long-term use of opioids, such as codeine, can alter the brain's reward system, increasing the potential for addiction. Continued use beyond prescribed dosage or duration carries a higher risk.

2. Respiratory Depression:

Codeine, an opioid pain reliever, may cause respiratory depression. This involves slowed or labored breathing. While severe respiratory depression is rare, the risk increases with higher doses and may be heightened by simultaneous use of other respiratory depressants like alcohol or other sedatives.

3. Liver Toxicity:

In certain individuals, including those with liver conditions or genetic variations, higher doses and long-term use of codeine may contribute to liver damage. Prolonged use and higher doses may stress the liver and potentially lead to drug-induced liver injury.

4. Gastrointestinal Problems:

Opioid medications, including codeine, can affect the digestive system. Some common side effects include constipation, nausea, vomiting, and upset stomach. In the long term, chronic constipation and reduced intestinal motility may become bothersome.

5. Tolerance and Reduced Effectiveness:

Tolerance may develop with extended use of codeine, necessitating higher doses to achieve the same level of pain relief. Eventually, the higher doses required may increase the risk of side effects.

6. Withdrawal Symptoms:

After prolonged use, abruptly stopping or drastically reducing codeine doses can lead to withdrawal symptoms. These typically manifest as increased sweating, headaches, agitation, tremors, muscle cramps, abdominal pain, diarrhea, and cravings for the drug. It's advisable to discuss any dose changes with your healthcare provider to avoid severe withdrawal.

Therefore, it is vital to discuss any concerns about the safety and long-term effects of codeine intake with a healthcare professional, especially if you have been taking 200mg twice a day for more than 4 years. Your doctor can assess your overall situation, determine whether codeine remains the best choice for managing pain, and make any necessary adjustments to reduce risks and preserve well-being.