How can we decrease ige level which is 420.?

There are several strategies that can be employed to decrease elevated immunoglobulin E (IgE) levels, including:

Immunotherapy: Immunotherapy, specifically allergen immunotherapy or desensitization, involves gradually exposing an individual to increasing amounts of the allergen that triggers their IgE response. Over time, this can help decrease the body's sensitivity to the allergen, leading to lower IgE levels.

Antihistamines: Antihistamines are medications that block the effects of histamine, a chemical released by the body during an allergic reaction. While antihistamines do not directly reduce IgE levels, they can alleviate allergy symptoms and may indirectly contribute to lower IgE levels by reducing the body's inflammatory response.

Leukotriene modifiers: Leukotriene modifiers are medications that block the effects of leukotrienes, other chemicals involved in allergic responses. Like antihistamines, leukotriene modifiers primarily manage allergy symptoms, but they may also have some impact on IgE levels.

Omalizumab (Xolair): Omalizumab is a monoclonal antibody medication specifically used to treat severe allergic asthma and chronic idiopathic urticaria (hives). It works by binding to IgE and preventing it from attaching to receptors on immune cells, thereby reducing the body's allergic response.

Other therapies: In some cases, additional therapies may be employed to decrease IgE levels, such as dietary modifications, probiotics, and lifestyle changes aimed at reducing overall inflammation.

It's important to note that the strategies mentioned here should be discussed with a healthcare professional, such as an allergist or immunologist, to determine the most appropriate approach based on an individual's specific condition and circumstances. The treatment plan for elevated IgE levels may vary depending on the underlying cause and underlying allergies, and personalized advice from a healthcare provider is essential.