How much tramadol can damage the liver?

The liver is responsible for metabolizing (breaking down) tramadol. However, taking high doses of tramadol or taking it for a long time can damage the liver. Liver damage can occur at doses as low as 200 mg per day, but it is more common at doses of 400 mg per day or higher.

The risk of liver damage increases with the dose and duration of tramadol use, as well as with the presence of other risk factors such as alcohol use, obesity, and diabetes.

Symptoms of liver damage can include:

* Nausea

* Vomiting

* Abdominal pain

* Jaundice (yellowing of the skin and eyes)

* Dark urine

* Light-colored stools

* Fatigue

* Weakness

* Loss of appetite

* Weight loss

If you experience any of these symptoms, it is important to see a doctor right away.

Here are some tips to help reduce your risk of liver damage from tramadol:

* Take the lowest dose possible of tramadol for the shortest amount of time necessary.

* Do not exceed the recommended dosage.

* Avoid drinking alcohol while taking tramadol.

* Talk to your doctor about your risk of liver damage if you have other risk factors such as obesity or diabetes.

If you have any concerns about liver damage from tramadol, it is important to talk to your doctor.