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What Happens From an Overdose of SMZ-MP DS?

Sulfamethoxazole trimethoprim double strength (SMZ-TMP DS) refers to a prescription drug that combines two antibiotics. The drug treats a variety of bacterial infections, such as middle ear infections, respiratory infections, and urinary tract infections. An overdose of SMZ-TMP DS is a serious medical emergency that can be fatal if untreated.

  1. Signs

    • Signs of an acute overdose include severe dizziness, drowsiness, nausea, vomiting or diarrhea, and mood changes.

    Treatment

    • If you overdose on SMZ-TMP DS, your stomach may be pumped. You may also receive intravenous (IV) fluids and other medications to help you recover.

    Long-Term Overdose

    • Long-term overdose of SMZ-TMP DS leads to bone marrow depression, which causes low red blood cell count, low platelet count and low white blood cell count, according to Drugwatch.com.

    Warning

    • If you suspect you or someone you know is suffering from an overdose, call your local emergency room and the national poison hotline at 1-800-222-1222.

    Considerations

    • If you forget to take a dose of SMZ-TMP DS, take it as soon as you remember, unless it is almost time for your next dose. Do not take a double dose of SMZ-TMP DS to catch up, since this may cause an overdose. Instead, skip the missed dose and take your normal dose.

    Side Effects

    • Regular doses of SMZ-TMP DS sometimes cause loss of appetite, nausea, vomiting, diarrhea or headache. Get emergency medical help if you experience seizures, confusion, neck stiffness, blood in your urine, muscle weakness, skin rash or breathing problems.

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