Skin Reaction to Quinine

Quinine is an alkaloid compound which occurs naturally in the bark of trees in the Cinchona family. For over 150 years, quinine has been used to protect against contraction of malaria, and also to treat contracted malaria in humans. Quinine is present in small doses in tonic water, or can be taken as a prescription medication. Skin reactions to quinine range from mild symptoms to serious allergic reactions.

Photosensitivity

• Quinine has a photosensitizing effect upon human tissue, including the skin. This means that taking quinine can increase the sensitivity of your skin to sunlight. Darkening of the skin, like a suntan, can occur over small or large areas when quinine is taken.

Flushing

• Flushing of the skin is one of the more common side effects of taking quinine. In isolation, skin flushing is only slightly inconvenient and is not cause for concern.

Allergic Reaction

• Certain individuals are allergic to quinine, and skin-related symptoms may be the first signs of a serious allergic reaction. If, after taking quinine, you develop a rash, hives, extensive itching or swelling of the mouth, lips, face or tongue, seek immediate medical help as these are signs of a likely allergic reaction to the drug.