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Medications That Cause Peyronie's Disease

A number of medications list Peyronie's disease as a possible side effect. However, according to the Cleveland Clinic, the chances that Peyronie's disease will develop from any of these medications are very low, and no evidence supports that these medications cause Peyronie's disease.

  1. Background

    • Peyronie's disease is the development of scar tissue, called plaque, along the length of the penis. This plaque may cause pain or bending in the penis when it's erect, making sexual intercourse difficult.

    Beta Blockers

    • Most of the drugs that list Peyronie's disease as a possible side effect are beta-blockers, which doctors often prescribe for people with heart conditions or high blood pressure.

    Interferon

    • Interferon is used to treat multiple sclerosis, according to the Cleveland Clinic. Its manufacturers list Peyronie's disease as a possible side effect.

    Dilantin

    • Dilantin is an anti-seizure medicine, according to the Cleveland Clinic. Its manufacturers list Peyronie's disease as a possible side effect.

    Expert Insight

    • According to the Mayo Clinic, the cause of Peyronie's disease is not known, but the disease may result from injury during intercourse, trauma to the penis from surgery, genetic factors or a problem with the immune system.

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