What causes a hive like rash that itch and goes away when sleeping but then comes back as the day on makes you fussy?

The rash you described could be caused by hives, also known as urticaria. Hives are raised, itchy skin welts that can appear anywhere on the body. They can be caused by a variety of factors such as allergies, infections, stress, and certain medications.

The itching and swelling associated with hives can be uncomfortable and disruptive to daily activities. Typically, hives last for a few hours or days, but in some cases they may persist for weeks or even months.

Here are some possible causes of hives that may be associated with sleep and irritability:

1. Allergies: Allergies to certain foods, medications, insect bites or stings, or environmental allergens such as pollen or dust mites can trigger hives. If you notice that your rash appears after exposure to a specific allergen, it is likely an allergic reaction.

2. Stress: Stress can also cause hives in some people. When you experience stress, your body releases certain hormones that can lead to the release of histamine, which is the chemical that causes the symptoms of hives.

3. Certain Medications: Some medications, such as aspirin, ibuprofen, and penicillin, have been known to cause hives as a side effect. If you are taking any new medications, it is worth considering the possibility that the hives may be a drug reaction.

4. Infection: Hives can sometimes be caused by infections, both viral and bacterial. Viral infections such as the common cold or flu can trigger hives, while bacterial infections such as strep throat or urinary tract infections can also be a cause.

If your rash persists or is accompanied by severe itching, swelling, difficulty breathing, or any other concerning symptoms, it is important to see a healthcare professional for evaluation and appropriate treatment.