What disease in children which an inefficient mineralization of the bone forming tissue causes deformities?

The disease in children which an inefficient mineralization of the bone forming tissue causes deformities is called rickets. Rickets is a condition that affects bone development in children, causing the bones to become soft and weak. It is caused by a deficiency of vitamin D, calcium, or phosphate. Vitamin D is necessary for the body to absorb calcium and phosphate from food. Calcium and phosphate are essential minerals for bone growth and strength.

Rickets is most common in children between the ages of 6 months and 2 years. It is more common in children who are not getting enough vitamin D from sunlight, breast milk, or formula. Children who are at risk for rickets include:

* Children who live in northern latitudes, where there is less sunlight

* Children who have dark skin, which makes it harder for them to absorb vitamin D from sunlight

* Children who are breastfed exclusively and do not receive vitamin D supplements

* Children who have a malabsorption condition, such as celiac disease or Crohn's disease

* Children who take medications that interfere with vitamin D absorption, such as steroids or anti-epileptic drugs

Symptoms of rickets can include:

* Bone pain

* Muscle weakness

* Delayed growth

* Deformities of the bones, such as bow legs or knock-knees

* Soft spots on the head (craniotabes)

* Enlarged joints

* Seizures

* Rickets can be diagnosed with a blood test that measures vitamin D levels and other minerals. X-rays may also be taken to look for signs of bone deformities.

Treatment for rickets includes taking vitamin D supplements. Calcium and phosphate supplements may also be necessary. Treatment usually lasts for several months until the child's bones have become strong and healthy.