Why is melatonin contraindicated in persons with autoimmune diseases?

There is no general contraindication for the use of melatonin in people with autoimmune diseases. Melatonin, a naturally occurring hormone primarily involved in regulating sleep-wake cycles, has generally been considered safe and well-tolerated. While research into melatonin's potential interactions with specific autoimmune conditions is ongoing, there is no established contraindication that prohibits its use in individuals with autoimmune diseases. If an individual has certain medical conditions or ongoing treatments, consulting with a healthcare professional before taking melatonin, or any supplement or medication, is always advisable to individualize their care and address any potential concerns.