What cause spondylitic?

Ankylosing spondylitis (AS) is a type of inflammatory arthritis that primarily affects the spine. The exact cause of AS is unknown, but it is thought to be related to genetic, immunological, and environmental factors.

Genetic factors: AS has a strong genetic component, with certain genes, such as HLA-B27, being associated with an increased risk of developing the condition. However, the presence of HLA-B27 does not guarantee that a person will develop AS, and many people with the gene never experience any symptoms.

Immune system dysregulation: AS is characterized by chronic inflammation of the joints and connective tissues, including the spine. This inflammation is thought to be caused by an overactive immune system that mistakenly attacks the body's own tissues.

Environmental factors: Certain environmental factors, such as infections and trauma, have also been suggested as potential triggers for AS. However, the exact role of these factors is not fully understood.

It is important to note that AS is not caused by poor posture, aging, or lifestyle choices. While these factors can contribute to back pain and stiffness, they do not cause the underlying inflammation and joint damage associated with AS.

If you are experiencing chronic back pain and stiffness, especially if it is accompanied by other symptoms such as fatigue, eye inflammation, or joint pain, it is essential to see a doctor for evaluation. Early diagnosis and treatment can help to manage the condition and prevent or slow down joint damage.