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Signs and Symptoms of Parry's Disease

Parry's disease is another term for Plummer's disease or a toxic nodular goiter, a type of condition in which nodules or growths appear on the thyroid gland. A number of symptoms are possible with Parry's disease, and as these symptoms are similar to other thyroid conditions, doctors rely on signs present in medical tests to diagnose the condition.

  1. Types of Symptoms

    • Symptoms of Parry's disease include fatigue, frequent bowel movements, heat intolerance, increased appetite, excessive sweating, menstrual irregularities, stomach cramps, nervousness, restlessness and weight loss.

    Time Frame

    • The symptoms of Parry's disease are most likely to develop in patients over the age of 60, reports the U.S. National Library of Medicine.

    Features

    • In some cases, symptoms of Parry's disease occur after a person receives an injection of iodine, which causes levels of thyroid hormone to increase rapidly, explains the U.S. National Library of Medicine. CT scans and heart catheterizations typically involve iodine injections for imaging purposes.

    Signs

    • With a physical examination, doctors usually feel the presence of nodules on the thyroid of those who suffer from Parry's disease, and radioactive imaging called a thyroid scan will show images of the nodules. A rapid heart rate and low amounts of thyroid stimulating hormone paired with high amounts of T3 and T4 thyroid hormones in blood work are additional signs of Parry's disease.

    Considerations

    • Abdominal pain, decreased mental alertness and fever, along with the symptoms of Parry's disease, are signs of a thyroid storm or crisis due to the presence of toxic nodular goiters. A thyroid storm is a medical emergency and requires prompt medical attention, warns the U.S. National Library of Medicine.

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