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What Causes a Peptic Ulcer?

According to the National Institutes of Health, one in 10 Americans will develop an ulcer in her lifetime. A peptic ulcer occurs when the lining of the stomach or small intestine and tissues beneath have been eroded, causing an internal open wound.

  1. Infection

    • Peptic ulcers were once thought to be caused by stress, but researchers now believe H. pylori infection is responsible for the majority of peptic ulcers. The bacteria weaken the protective coating, allowing acid and bacteria to get through.

    Risk Factors

    • Researchers are uncertain how H. pylori is contracted, but many suspect it is spread through food and water.

    Drug Risks

    • Long-term use of non-steroidal anti-inflammatory drugs like aspirin and ibuprofen has been linked to peptic ulcers.

    Diagnosis/Treatment

    • Peptic ulcers can be detected by x-ray or endoscopy, and if ulcers exist, blood tests are used to detect H. pylori bacteria. Treatment usually involves a combination of drugs, including antibiotics, acid suppressors and stomach protectors.

    Prognosis

    • According to Dr. James F. Balch, at least 90 percent of peptic ulcers can be cured with appropriate treatment, but complete healing may take eight weeks or more.

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