Estriol Cream & Bacteria Infection

Estriol is a hormone used in post-menapausal women to treat vaginal dryness. It is also used to treat urinary tract infections (UTIs) caused by bacteria. Estriol comes in pill or cream form, but in cases of UTIs, it's often given as a cream and applied regularly to eliminate and prevent the recurrence of infection.

• Estriol is a Treatment for UTIs

Significance

• Estriol is one of the three estrogens that circulates in the body. It's produced in higher levels during pregnancy. Post-menopausal women who have lowered estriol levels lose lactobacilli in the vagina. This condition allows pathogens to colonize the urinary tract, causing infection.

Function

• Estrogen is used to promote the development of secondary sex characteristics in women like breasts and control of the menstrual cycle. Estriol maintains the health of the vaginal microbes that destroy pathogens like bacteria.

Structure

• Estriol is produced from cholesterol. Cholesterol is a ring structure that is insoluble. Cholesterol is created by the liver, and it's obtained from the diet.

Types

• There is one current drug in phase four clinical trials tested for post-menopausal women and treatment of UTIs. Gynoflor E contains low doses of estriol and lactobacillus, the bacteria located in the vagina that maintains its health.

Dose

• Estriol is given to patients in a cycle. The patient is asked to take one pill twice a day or apply cream twice a day for a period of 18 days.