Can prednisone cause urinary tract infection?

Yes, prednisone can cause urinary tract infection (UTI).

Prednisone is a corticosteroid medication used to treat various inflammatory conditions. Urinary tract infection is a common infection that can affect the kidneys, ureters, bladder, and urethra. While prednisone is not directly linked to causing UTIs, certain factors related to its use can increase the risk of infection.

Here's how prednisone can contribute to the development of a UTI:

1. Immunosuppression: Prednisone is an immunosuppressive medication, meaning it suppresses the body's immune system. This can make individuals more susceptible to various infections, including UTIs. A weakened immune system may be less effective at fighting off bacteria that enter the urinary tract.

2. Increased Blood Sugar: Prednisone can raise blood sugar levels in some people, especially if taken for a prolonged period. High blood glucose can provide a suitable environment for bacteria to thrive and multiply, including those that can cause UTIs, such as E. coli.

3. Changes in Urinary System Function: Prednisone may affect the normal functioning of the urinary system. It can cause increased urine output and frequency of urination. Frequent urination may flush out beneficial bacteria from the urinary tract, disrupting the natural balance of microorganisms and increasing the risk of infection.

4. Delayed Wound Healing: Prednisone can slow down wound healing processes. This effect may extend to the urinary tract as well. If there are any injuries or trauma to the urinary system, prednisone can delay healing, allowing bacteria to invade and establish an infection.

5. Concurrent Conditions: Prednisone is often used to treat various inflammatory conditions, some of which may also increase the risk of UTIs. For instance, patients with diabetes, an underlying condition commonly managed with prednisone, are already more prone to UTIs due to high sugar levels.

It is important to note that not everyone taking prednisone will experience a UTI, but the aforementioned factors can increase the likelihood of infection. Individuals taking prednisone, particularly for long-term therapies or high doses, should be aware of these potential risks and practice good hygiene to prevent UTIs.

If you are prescribed prednisone and develop symptoms of a UTI, such as frequent urination, pain or burning sensation while urinating, cloudy or foul-smelling urine, or fever, it is essential to consult your doctor promptly. Early diagnosis and appropriate antibiotic treatment can help resolve the infection and prevent further complications.