Why would insulin not bring down a high sugar reading?
Several factors can prevent insulin from effectively lowering a high sugar reading:
Insulin Resistance: Insulin resistance occurs when the body's cells become less responsive to the effects of insulin. In this condition, even normal amounts of insulin may not be able to effectively transport glucose from the blood into the cells. As a result, blood sugar levels remain high despite insulin administration.
Inadequate Insulin Dose: If the dose of insulin administered is insufficient, it may not be enough to overcome insulin resistance or the elevated blood sugar levels. This can occur if the initial insulin dose is not properly calculated based on the individual's insulin sensitivity and the severity of hyperglycemia.
Poor Insulin Absorption: Factors that affect the absorption of insulin from the injection site can also impact its effectiveness. These factors may include scar tissue at the injection site, incorrect injection technique, or improper insulin storage. In such cases, the insulin may not be fully absorbed, leading to reduced efficacy.
Hepatic Insulin Clearance: The liver plays a role in clearing insulin from the bloodstream. In certain conditions such as liver disease or high levels of certain hormones (e.g., growth hormone), the liver's ability to remove insulin from the circulation may be increased. This can result in a shorter duration of insulin action, leading to less effective blood sugar control.
Other Hormonal Influences: Certain hormones, including adrenaline and cortisol, can elevate blood sugar levels. In situations where these hormones are elevated (e.g., during stress, intense exercise, or illness), insulin may be less effective in lowering blood sugar.
Pancreatitis: Inflammation of the pancreas (pancreatitis) can affect the production and secretion of insulin. If insulin production is significantly reduced or absent, exogenous insulin may be required to manage high blood sugar effectively.
Errors in Insulin Administration: Incorrect storage, mixing, or administration of insulin can affect its potency and effectiveness. Factors such as using expired insulin, exposing it to extreme temperatures, or mixing different insulin types can lead to reduced insulin activity.
If a high sugar reading persists despite insulin administration, it is important to consult with a healthcare professional to evaluate the underlying factors and adjust the insulin regimen or treatment plan as needed to achieve effective blood sugar control.