Gastric protease operates most efficiently in the presence of hydrochloric acid Which pH range would be optimal for gastric protease?

Gastric protease, also known as pepsin, is a digestive enzyme that is produced by the chief cells of the stomach. It is active in the highly acidic environment of the stomach, with an optimal pH of around 1.5 to 2.0. At this pH, pepsin is able to cleave peptide bonds in proteins, breaking them down into smaller molecules that can be absorbed by the body.

The acidic environment of the stomach is created by the hydrochloric acid that is secreted by the parietal cells. Hydrochloric acid helps to denature proteins, making them more susceptible to digestion by pepsin. It also activates pepsinogen, the inactive form of pepsin, converting it into the active form.

Therefore, the optimal pH range for gastric protease is between 1.5 and 2.0, which is the pH range of the stomach.