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The Effects of Prilosec on Calcium

Prilosec (omeprazole) is a medication used to reduce stomach acid, which in turn relieves the pain and problems associated with acid reflux. Studies of elderly women have shown a decrease in calcium absorption coinciding with the administration of Prilosec.

  1. Prilosec

    • Omeprazole is a member of the family of drugs known as proton pump inhibitors. These work to block production of stomach acid, which can cause damage ranging from gastric and duodenal ulcers to gastroesophageal reflux disease (see Reference 1).

    Calcium Absorption

    • Calcium malabsorption can be connected to the intake of Prilosec because hydrochloric acid, which is reduced with Prilosec, is a necessary component for the body's ability to absorb calcium (see Reference 2).

    Calcium Citrate

    • While the absorption of calcium carbonate is shown to decrease when paired with omeprazole, early studies have shown that calcium caltrate absorption is not hindered by the use of Prilosec (see Reference 3).

    Age and Absorption

    • In a 2002 double-blind study in elderly women at the University of Minnesota, a correlation was found between age and ability to absorb calcium while on omeprazole. As a person aged, her ability to absorb calcium declined (see Reference 2).

    Uses for Calcium

    • While calcium is mainly associated with maintaining the strength of the bone structure, it also aids with muscle contraction, blood vessel expansion and contraction, secretion of hormones and enzymes, and transmitting nervous system impulses.

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