Is Absorption of Medication Effected by Alli?

Alli is an over-the-counter medication used for weight reduction. The generic name for Alli is orlistat. Alli works by blocking some of the fat you consume from being absorbed in your digestive tract. Some medications are affected by this action and their effectiveness may be decreased.

How Medication is Absorbed By the Body

• When medications are taken orally, by mouth, they move through the digestive tract and enter the blood stream. The medications then travel to the liver where they are metabolized and distributed through the body once again through the blood stream.

Actions of Alli In the Digestive Tract

• Alli blocks the enzyme lipase, which is responsible for breaking down the fat you eat for use by the body. Lipase is found in the digestive tract. Alli works in the digestive tract by aiding in the elimination of fat through your bowels.

Alli and Cyclosporine

• Cyclosporine is given to organ transplant patients. Myalli.com reports that Alli may interfere with the absorption of cyclosporine.

Alli and Warfarin

• Warfarin is a blood-thinner. It is commonly used by people who have heart disease or are at an increased risk for strokes. According to the website for Alli, Myalli.com, absorption of Warfarin may be affected by taking Alli.

Other Medications

• Oral medications for diabetes and thyroid medications may be affected by Alli. Myalli.com recommends that if you are taking either types of these medications, that you consult with your doctor before you take Alli as your medication dosages may need to be adjusted.