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Does Phentermine Cause Depression?

There is some speculation as to whether the drug Phentermine, commonly used as a weight loss aid in many supplements, is a catalyst for increasing depression in some individuals. Phentermine has been approved for use as a dietary supplement by the Food and Drug Administration, and it is widely accepted as a safe drug in the battle against obesity. The question is, do the benefits outweigh the risks?

  1. History

    • Phentermine is commonly used for weight loss in individuals who are suffering from mild to moderate obesity. It is sold under a wide variety of names and comes in tablet or capsule form. Phentermine releases a chemical that suppresses appetite by increasing stimulation of the nervous system and can cause an increase in heart rate along with the decrease in appetite. A link has been found between the use of Phentermine and depression in some individuals, possibly due to a disruption in serotonin levels in the brain.

    Considerations

    • Serotonin is a mood regulator that occurs naturally in the body. When serotonin levels are chemically altered, as they are with the use of diet supplements such as Phentermine, a chemical imbalance occurs that may lead to feelings of anxiety or depression. With long-term Phentermine usage, serotonin levels may not return to a normal level, thereby increasing depression risk indefinitely.

    Benefits

    • Individuals who suffer from obesity may be at an increased risk of heart attack, stroke and other life-threatening illnesses. Because of this, they may feel that the benefits of taking Phentermine, including decreased appetite and increased weight loss, outweigh the risks. This is an individual choice that should be discussed with a physician.

    Risks

    • While taking Phentermine for weight loss, individuals should stay in close contact with a physician. If feelings of depression or anxiety occur, users should immediately stop using Phentermine and contact the physician for further options.

    Potential

    • The Food and Drug Administration (FDA), continues to study Phentermine and monitor the side effects associated with its usage.

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