Does Tamoxifen Cause Weight Gain?

Yes, Tamoxifen can cause weight gain as a side effect.

Tamoxifen is a selective estrogen receptor modulator (SERM) that is used in the treatment of breast cancer. It works by blocking the effects of estrogen in breast tissue. Tamoxifen can also cause side effects such as hot flashes, vaginal dryness, and nausea.

Weight gain is a common side effect of tamoxifen. It is thought to be caused by the drug's effect on estrogen levels. Estrogen can help to regulate body weight, and when estrogen levels are lowered, weight gain can occur.

The amount of weight gain that a person experiences can vary. Some people may gain only a few pounds, while others may gain more. Weight gain is usually gradual and occurs over time.

If you are concerned about weight gain while taking tamoxifen, talk to your doctor. There are things that you can do to help manage your weight, such as eating a healthy diet and getting regular exercise.