Will doxepin make you gain weight?

Possible, But Usually Not a Significant Concern

While it is possible to gain weight while taking doxepin, this is not usually a significant concern. In fact, some studies have even shown that doxepin can actually cause weight loss, possibly because it reduces appetite. That said, doxepin may increase food cravings in some people and lead to weight gain.

Talk to your doctor if you are worried about weight gain or any other side effects of doxepin. They can help you monitor your weight and make adjustments to your medication or lifestyle as needed.