What is the ratio of babies getting tay-sachs disease?

The incidence of Tay-Sachs disease varies among different populations. Here are some general estimates:

1. Ashkenazi Jewish Population: Tay-Sachs disease is most common in the Ashkenazi Jewish population. The carrier frequency (the percentage of individuals who carry one copy of the Tay-Sachs disease gene) is approximately 1 in 30. Consequently, the risk of having a child with Tay-Sachs disease for a couple where both partners are Ashkenazi Jewish is about 1 in 3,600.

2. Non-Ashkenazi Jewish Population: Tay-Sachs disease is rare in non-Ashkenazi Jewish populations. The carrier frequency is generally much lower, although it can vary among different ethnic groups.

Please note that these estimates are approximate and may vary based on specific regions and populations. If you have concerns about Tay-Sachs disease or carrier status, it is recommended to consult with a healthcare professional or a genetic counselor for accurate information and guidance.