Can you tell from blood types if all siblings come the same mother and father?

Blood types alone cannot definitively determine if all siblings come from the same mother and father. Multiple factors influence blood type inheritance. Here's why:

Genetic Variation: Blood type is determined by specific genes inherited from both parents. There are several blood group systems, including the ABO blood group and Rh blood group. Each system has multiple alleles (different forms of the gene) that determine the type of blood an individual carries.

Incomplete Dominance: In the ABO blood group system, the A and B alleles are dominant, while the O allele is recessive. This means that an individual with at least one dominant allele (A or B) will express the corresponding blood type, while two copies of the recessive allele (OO) will result in the O blood type.

Multiple Alleles: The Rh blood group system involves two alleles, the R (positive) and r (negative) alleles. An individual with at least one R allele (RR or Rr) will be Rh-positive, while individuals with two r alleles (rr) will be Rh-negative.

Parent-Child Relationships: Analyzing the blood types of parents and children can provide some insights into their genetic relationship, but it's not a definitive proof. For instance:

- If both parents are Rh-negative (rr), all of their children will be Rh-negative.

- If one parent is Rh-positive (RR) and the other is Rh-negative (rr), all of their children will be Rh-positive (Rr).

- If both parents are Rh-positive (RR or Rr), their children can be either Rh-positive or Rh-negative, depending on the specific alleles they inherit.

Sibling Relationships: Similarly, analyzing the blood types of siblings can provide some clues about their genetic relationship, but it doesn't guarantee that they all come from the same biological parents. For example:

- If two siblings have the same rare blood type, such as AB-negative, it's more likely that they share the same biological parents.

- If two siblings have different blood types, such as one being A-positive and the other being O-negative, it doesn't necessarily mean they don't share the same biological parents. It could be possible based on the genetic variations they inherited from their parents.

DNA Testing: In cases where precise determination of genetic relationships is required, DNA testing is the most accurate method. DNA analysis can confirm whether individuals are full siblings (sharing both biological parents), half-siblings (sharing one biological parent), or not related at all.

In summary, while blood types can provide some indications of genetic relationships, they are not sufficient on their own to conclusively determine if all siblings come from the same biological mother and father. DNA testing is the gold standard for establishing accurate biological relationships.

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