Im pregnant and you have cystic fibrosis what are the chances of my child getting CF?
Cystic fibrosis (CF) is an autosomal recessive genetic disorder, which means that both copies of the CFTR gene must be mutated in order for a person to have the disease. If you are pregnant and have CF, the chances of your child inheriting CF depend on the genetic status of your partner:
- If your partner does not have CF and does not carry the CF mutation, the chances of your child having CF are very low, close to 0%.
- If your partner is a carrier of the CF mutation, which means they have one mutated copy of the CFTR gene and one normal copy, the chances of your child inheriting CF are 50%. In this case, each pregnancy has a 50% chance of resulting in a child with CF and a 50% chance of resulting in a child who is a carrier but does not have the disease.
- If your partner has CF, which means they have two mutated copies of the CFTR gene, the chances of your child inheriting CF are 100%. In this case, all children born to a parent with CF will have CF.
It's important to discuss your family's genetic history and the potential risks with a genetic counselor or healthcare professional who specializes in CF.