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Can an Overactive Thyroid Effect PSA Levels?

PSA, or prostate-specific antigen, is a protein produced by the prostate gland. Elevated PSA levels in the blood are associated with dangerous prostate changes, but an overactive thyroid is not typically indicated.

  1. The Facts

    • The prostate is a small gland near the bladder that forms components of seminal fluid. The thyroid is a small gland near the front of the lower neck that produces hormones that help control your metabolism.

    Uses of PSA Testing

    • According to the National Cancer Institute, checking PSA levels detects the possible occurrence of prostate cancer, as well as benign prostatic hyperplasia (BPH, or enlarged prostate) and prostate inflammation (prostatitis).

    Factors Affecting PSA Levels

    • Apart from cancer, BPH and prostatitis, factors known to influence PSA levels include age, obesity, recent ejaculation, heightened physical activity and certain chemotherapy drugs and nonprescription products for prostate health. Overactive thyroid is not a known factor.

    Considerations

    • Although changes in PSA levels may indicate prostate disease, controversy exists over the risks and benefits of treatments resulting from PSA testing.

    Recommendations

    • The American Cancer Society does not support regular testing to detect prostate cancer, and urges health care professionals to discuss the limits of testing with their patients.

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