What are a toddler aPTT values with hemophilia A?

The normal activated partial thromboplastin time (aPTT) reference range for a toddler is approximately 25 to 35 seconds. However, if a toddler has hemophilia A, their aPTT value may be significantly prolonged, indicating a deficiency or dysfunction of clotting factor VIII, which is essential for normal blood clot formation.

In individuals with severe hemophilia A, the aPTT value can be markedly elevated, often exceeding 100 seconds. This prolonged clotting time reflects the insufficient amount or activity of factor VIII, which leads to impaired blood clot formation and an increased tendency for bleeding.

It's important for toddlers with suspected or diagnosed hemophilia A to undergo regular monitoring of their aPTT levels and other coagulation parameters to assess their clotting function and guide appropriate treatment strategies.