Allegra Effect on Bipolar Disorder

Allegra is a second generation antihistamine that treats the symptoms of allergic rhinitis, including runny nose and congestion. Compared to first generation antihistamines, Allegra has a low occurrence of the side effects that can exacerbate the symptoms of bipolar disorder, a condition marked by the cycling of mood states from depression to mania.

Depression

• While Allegra's potential for triggering depression was determined by the FDA as lower than that of the first generation antihistamines, it remains a risk. Out of 14,753 reports of adverse effects of Allegra compiled by EHealthMe.com, 3.6 percent cited depression.

Mania

• Some symptoms, such as excitability and restlessness are also signs of mania, at the other end of the bipolar spectrum. Another symptom, agitation, was reported by over one percent of the respondents on EHealthMe.com.

Impaired Thinking

• According to Drugs.com, Allegra can trigger reactions that seriously affect mental processes, such as hallucinations or unusual thoughts and behavior, all of which are consistent with bipolar disorder.

Drug Interactions

• Consult your psychiatrist before taking Allegra.

  Many people treat symptoms of bipolar disorder with prescription drugs. Inform your medical practitioner and psychiatrist if you take Allegra, as an interaction can worsen those symptoms.

Women and Vasomotor Rhinitis

• A study cited by WebMd reports that women with vasomotor rhinitis have higher occurrences of anxiety and depression. Vasomotor rhinitis is a type which is not caused by allergens, but shows similar symptoms and is commonly treated with the same medicines, including Allegra.