Connection Between Bipolar Disorder & Cushing's Syndrome

Bipolar disorder, characterized by mood swings between depression and mania, is oftentimes confused with Cushing's Syndrome. The syndrome causes irregularities in mood and behavior resulting in depression, and oftentimes is mistaken for bipolar disorder.

Cushing's Syndrome

• The Mayo Clinic states that "Cushing's Syndrome is a condition that occurs when your body is exposed to high levels of the hormone cortisol for a long time." Cushing's causes weight gain, depression and anxiety, and it requires oral corticosteroid medication.

Bipolar Disorder

• Bipolar disorder presents with similar symptoms as Cushing's including depression and anxiety; however, oral corticosteroid medication is ineffective.

Correlation

• According to Unbound Medline, patients with Cushing's were treated as bipolar and then became symptom free after having a tumor (often associated with Cushing's) removed, lowering the hormone cortisol in the body.

Misdiagnosis

• If you have been diagnosed with bipolar and have the symptoms of Cushing's Syndrome, consult with your physician immediately.

Tips

• Be sure to avoid taking bipolar medications for Cushing's or vice versa. If you experience symptoms of both, a physician should be able to distinguish between the two.