What Triggers Manic-Depression?

Manic-depression is a mental illness that is now known as bipolar disorder. This mood disorder causes extreme mood changes from highs (mania) to lows (depression). While manic-depression is a chronic disorder, there are triggers that can bring about the symptoms. The triggers can worsen existing symptoms or bring about new manic or depressive episodes.
  1. Stress

    • Any stress -- good or bad -- can trigger the symptoms. Severe financial difficulties, job loss, getting married, a breakup, a windfall or a serious illness can bring about manic-depression.

    Drug and Alcohol Abuse

    • The Mayo Clinic states that "Drugs such as cocaine, ecstasy, and amphetamines can trigger mania, while alcohol and tranquilizers can trigger depression."

    Change of Season

    • For some people, the weather affects mood. Mania is more common in the summer, while depression is more frequent in the winter months.

    Brain Chemistry Changes

    • There are over 100 chemicals in the brain called neurotransmitters that affect mood. As the levels of these chemicals fluctuate, a manic or depressive episode can be triggered.

    Lack of Sleep

    • Sleep deprivation or trouble staying asleep can trigger bipolar symptoms.

    Hormonal Changes

    • While some women experience moodiness during their periods, in some cases, the hormonal fluctuations trigger manic-depressive symptoms in women who already suffer from the disease.

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