About Depakote's Long-Term Risks
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Irregular Menstruation
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Long-term Depakote use has also been linked to irregular menstruation.
PCOS
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Some women using the drug over a long period of time have been known to develop PCOS, or polycystic ovary syndrome.
Bone Loss
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Bone loss is a side effect of taking Depakote for many years. Supplements such as calcium and vitamin D can combat this.
Bone Density Test
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Depakote users should talk to their doctors about getting a bone density test if they have been taking the drug for more than 5 years.
Solution
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Any side effect that becomes intolerable, difficult to deal with or detrimental to the quality of life should be discussed with a qualified medical professional.
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