Sleep Disorders Related to Low Serotonin

Serotonin is a hormone (also known as 5-hydroxytryptamine) found in the pineal gland, digestive tract, blood platelets and brain, where it works as a neurotransmitter that sends nerve signals between nerve cells. If an individual does not have enough serotonin in her body she may develop health problems such as having difficulty sleeping.

• Serotonin helps regulate sleep.

Serotonin's Significance

• Low levels of serotonin have been suspected as a culprit in depression and other mood disorders, and it is believed to contribute to sensitivity to light and noise. It may also be a contributing factor in muscle weakness due to fibromyalgia. All of these symptoms can contribute to sleep difficulties.

Serotonin and Sleep

• Some sleep disturbances are a result of depression or environmental symptoms caused by low levels of serotonin, but the low level of the hormone itself may cause sleep problems. This is because serotonin plays a part in the onset and regulation of sleep. Consequently, an individual who does not have enough serotonin in her body will require more time to fall asleep and may not sleep deeply.

Other Ways Serotonin Affects Sleep

• Serotonin helps relieve pain and decreases appetite. Consequently, an individual with a shortage of serotonin may struggle with sleep because of pain or hunger.

Evidence

• A June 2006 study reported in "Science Daily" found that pharmacological intervention of serotonin significantly improved the amount and quality of sleep, evidence that the substance is vital to getting proper rest. The study was performed on fruit flies because they have a very simple nervous system.

Warning

• Sleep is necessary for health, mood, pain management and thinking and processing ability. If you are having difficulty falling or staying asleep or feeling refreshed when you awaken, consult your physician. While it is not possible to measure serotonin levels, she can study your symptoms and work with you to find an effective treatment, which may include medication to regulate the amount of the substance in your body.