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What Is SSRI Medication ?

Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants. SSRI medications may provide mood boosting effects for people suffering from depression.

  1. Serotonin

    • Serotonin is a neurotransmitter that affects mood, appetite and sleep. According to MayoClinic.com, mood and behavior may be affected by abnormalities in neurotransmitter activity. SSRIs work by inhibiting the reabsorption of serotonin, thus leaving more serotonin available in the brain.

    Types

    • Multiple SSRIs are approved by the FDA for the treatment of depression. Prozac, Lexapro, Celexa, Paxil and Zoloft are commonly prescribed for depression.

    Therapeutic Effects

    • SSRIs are typically used to alleviate symptoms of extreme sadness, hopelessness and lack of interest in activities, according to HealthyPlace.com. They are also commonly prescribed for general anxiety disorder.

    Side Effects

    • Patients may experience nausea, sexual dysfunction, dry mouth, increased sweating, weight gain, drowsiness or restlessness when taking an SSRI. Side effects are generally worse when first beginning or increasing the medication. While each SSRI has similar possible side effects, each may affect individual people differently.

    Serotonin Syndrome

    • Rarely, SSRIs may actually increase serotonin levels too much, resulting in serotonin syndrome. Anyone experiencing confusion, extreme agitation, and vomiting should seek medical attention immediately.

    Other Warnings

    • According to MayoClinic.com, Paxil may be associated with an increase risk of birth defects if taken during the first trimester of pregnancy. Women who are planning to become pregnant should talk to their physician about switching to another antidepressant. SSRIs may cause withdrawal symptoms if stopped abruptly and should gradually be tapered off. SSRIs may actually worsen symptoms in people ages 18 to 24 during when treatment is first started. Because of increased suicide risk, closer monitoring may be required.

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