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What Are the Functions of an SSRI?

The Selective Serotonin Reuptake Inhibitor (SSRI) is the most drug.popular class of antidepressant prescribed today. It is considered to have fewer side effects than other medications, but some believe they are not as effective in treating major depression as an SNRI. Ultimately, a person should consult a medical professional before taking an SSRI, or any prescription

  1. How SSRI's Function

    • While it's not clear exactly how SSRI's operate, it is believed that they act on the serotonin neurotransmitters in the brain. Serotonin is believed to be the chemical responsible for "mood", among other things. By decreasing the re-uptake (or re-absorption) of this chemical in the brain, SSRI's are said to improve one's mood.

    Protection

    • In addition to blocking the re-absorption of serotonin in the brain, SSRI's are said to play a protective role. By keeping nerve cells strong against a chemical called glutamate, it is thought that SSRI's help alleviate the problems of depression and anxiety.

    SSRI vs. SNRI

    • While SSRI's are the most popularly prescribed of antidepressants, SNRI's (Serotonin-Norepinephrine Inhibitors) are also said to be effective in combating illnesses such as depression. SNRI's are thought to function on the neurotransmitter norepinephrine, in addition to serotonin. Norepinephrine is thought to be the chemical responsible for mental energy and alertness. Some doctors feel this class of antidepressant is more effective in treating major depression, but this is controversial, and SNRI's are thought to have more side effects.

    Side Effects

    • People have reported a number of side effects when taking SSRI's. These include, nausea, headache, dry mouth, nervousness, rash, drowsiness, agitation, restlessness, insomnia, diarrhea, and more.

    Prescription

    • Before taking an SSRI, or any prescription medication, it's important to consult a medical professional. Each individual has his own biological needs, and drugs such as SSRI's and SNRI's function differently in different people.

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