Does St. Wort produce anxiety?

Anxiety: Some people report feeling anxious or restless when taking St. John's wort, especially in high doses.

Anxiety is one of the most common side effects of St. John's wort, and it can range from mild to severe. Some people may also experience irritability, jitteriness, and difficulty concentrating. If you experience any of these side effects, you should talk to your doctor about reducing the dose or switching to another medication.